Resources

Proteomics Databases



Metabolomics Databases

• • Principle of Fusion Protein Interaction Analysis Using Pull-Down and MS

  Protein-protein interactions are fundamental to cellular biology, playing critical roles in regulating cellular functions, signaling pathways, and metabolic processes. Understanding these interactions can shed light on biological mechanisms and provide new targets and strategies for disease research. Pull-down techniques combined with mass spectrometry (MS) analysis offer a powerful approach to studying fusion protein interactions.

• • Analysis of Bone Tissue Protein Properties

  Bone tissue, as an important support structure of the human body, relies heavily on its internal protein components for stability and functionality. Proteins play a key role in bone formation, remodeling, and mechanical properties. Therefore, in-depth analysis of the properties of bone tissue proteins can provide valuable information for bone health, disease treatment, and bone regeneration.

• • Protein Analysis of Liver Tissue

  The liver, the second largest organ in the human body after the skin, is responsible for various physiological functions such as metabolism, detoxification, bile secretion, and production of plasma proteins. Its health is directly related to the normal functioning of the body. Understanding the liver proteome and its changes is essential for the diagnosis, treatment, and prevention of liver diseases. The role of proteins in cells is not limited to being structural materials.

• • Mechanism of De Novo Sequencing

  De Novo sequencing is a genome sequencing method that does not rely on reference genome sequences and is mainly used for the assembly and annotation of new species genomes. With the advancement of high-throughput sequencing technology, De Novo sequencing has played an essential role in biological research.

• • Application of De Novo Sequencing

  De Novo sequencing refers to assembling a complete genome sequence from scratch without using a reference genome. This method is vital in genomic research, especially for exploring unknown genomes, complex genomes, and genomic diversity.

• • Workflow of De Novo Sequencing

  De Novo sequencing, also known as whole genome assembly, involves obtaining a novel genome sequence by direct sequencing and subsequent assembly without any reference genome information. This technology is crucial in genomics research and is widely utilized for discovering unknown genomes, analyzing new species' genomes, and studying complex genomic structures.

• • Advantages and Disadvantages of De Novo Sequencing

  De Novo sequencing refers to sequencing and assembling an unknown genome without a reference genome. With the rapid development of high-throughput sequencing technologies in recent years, De Novo sequencing has played an increasingly important role in life sciences research.

• • Principle of De Novo Sequencing

  With the advancement of genomics, genome sequencing technology has become a crucial tool in biological research. Among various sequencing technologies, De Novo sequencing is particularly significant because it does not rely on existing reference genomes and can reveal entirely new genomic information.

• • Mechanism of Top-Down Protein Sequencing

  Proteins are essential molecules in all biological processes. Understanding their structure and function is fundamental to biological research. Protein sequencing, which determines the amino acid sequence of proteins, is a crucial technique for studying the relationship between protein structure and function. Top-down proteomics is an emerging technique that is becoming a significant tool in protein sequencing.

• • Application of Top-Down Protein Sequencing

  Proteins are the primary executors of biological activities, and understanding their structure and function is crucial for uncovering biological mysteries. Protein sequencing, a vital research tool, helps scientists identify and analyze amino acid sequences of proteins, thereby inferring their functions and interactions. Top-Down Proteomics (TDP) is an advanced and precise protein sequencing technology developed in recent years.