Comprehensive Services2

• • Glycoprotein Modifications Analysis Service

  Glycoprotein modifications analysis services use advanced mass spectrometry techniques to accurately analyze the glycosylation modifications on glycoproteins, revealing their types, sites, and changes under different biological conditions. Glycosylation, as an important regulatory mechanism for protein function, directly affects the structure, stability, and biological functions of glycoproteins, especially in processes such as cell recognition, signal transduction, and immune response. Glycoprotein modif

• • Glycoprotein Interaction Analysis Service

  Glycoprotein interaction analysis service is primarily used to study the interactions between glycoproteins and other biomolecules, such as proteins, lipids, and nucleic acids. These interactions often play a crucial role in the occurrence and progression of various diseases, particularly in cancer, viral infections, and immune-related disorders. Through glycoprotein interaction analysis, researchers can uncover the impact of glycosylation on protein function, providing valuable insights for drug developmen

• • Glycoprotein Biomarker Discovery Service

  Glycoproteins are complex molecules formed by the covalent linkage of proteins and glycans, widely distributed on cell surfaces and in body fluids. They play critical roles in key physiological processes, including cell recognition, signal transduction, and immune regulation. Glycoproteins display highly diverse glycosylation patterns, and alterations in their structure and function are strongly associated with diseases such as cancer, cardiovascular disorders, and neurodegenerative diseases. These disease-

• • Glycoprotein Quantitation Service

  Glycoprotein quantification involves measuring the levels of glycosylated proteins in biological samples. Glycosylation is a crucial post-translational modification where sugar molecules covalently attach to proteins, influencing their structure, function, stability, and intercellular interactions. Alterations in glycosylation patterns are strongly associated with various diseases, including cancer, diabetes, and autoimmune disorders. Quantitative analysis of glycoproteins aids in elucidating disease mechan

• • Native N-glycome profiling Service

  N-glycome profiling involves the qualitative and quantitative determination of N-glycan structures on proteins without undergoing chemical derivatization. N-glycan chains are complex glycosylation modifications formed by the covalent attachment of asparagine (Asn) residues to proteins. These modifications are widely present on cell surfaces and in secreted proteins, influencing protein stability, function, and protein-protein interactions. Traditional N-glycan analysis often requires derivatization of glyca

• • Custom Glycoprotein Analysis Service

  Currently, glycoprotein analysis is experiencing rapid development, particularly with the application of mass spectrometry and chromatography techniques. However, there are still shortcomings, such as technical complexity, sample heterogeneity, and a lack of standardized methods, which affect the accuracy and reproducibility of data. Furthermore, existing analysis methods often fail to meet specific research needs, limiting the in-depth understanding of glycosylation functions. Custom glycoprotein analysis

• • Protein Identification by LC-MS/MS Service

  MtoZ Biolabs offers Protein Identification by LC-MS/MS Service, enabling precise identification and analysis of proteins from complex biological samples. Protein identification is fundamental to life sciences research, with applications spanning protein function analysis, cellular metabolism, signaling pathway exploration, and biomarker discovery. Accurate protein identification is critical for advancing disease research, drug development, and metabolomics.

• • Hybridoma Antibody Sequencing Service

  Hybridoma technology has been a cornerstone in the development of monoclonal antibodies, offering the ability to generate highly specific antibodies for research, diagnostics, and therapeutic applications. However, to fully leverage the potential of hybridoma-derived antibodies, it is essential to obtain the underlying genetic information that defines their structure and specificity. Hybridoma Antibody Sequencing Service addresses this need by extracting the antibody genes from hybridoma cells and...

• • Single-Molecule Protein Sequencing Service

  At MtoZ Biolabs, we provide a state-of-the-art Single-Molecule Protein Sequencing Service based on mass spectrometry (MS), offering an unparalleled level of sensitivity and precision in proteomics analysis. This innovative technique captures data from individual protein molecules, bypassing the need for protein digestion or peptide fragmentation, and allows for the sequencing of intact proteins in their native forms.

• • Protein De Novo Sequencing Service

  In the ever-evolving landscape of proteomics, the ability to accurately determine amino acid sequences without prior knowledge of the protein structure is paramount for elucidating their functions, interactions, and roles in various biological processes. MtoZ Biolabs is at the forefront of this scientific frontier, offering comprehensive Protein De Novo Sequencing Services tailored to meet the intricate demands of contemporary biological research and therapeutic development.